| Nicotine is named
after the tobacco plant Nicotiana tabacum, which in turn is
named after Jean Nicot, French ambassador in Portugal, who sent
tobacco and seeds from Brazil to Paris in 1550 and promoted
their medicinal use. Nicotine was first isolated from the
tobacco plant in 1828 by German chemists Posselt & Reimann.
Its chemical empirical formula was described by Melsens in 1843,
and it was first synthesized by A. Pictet and Crepieux in 1893.
Nicotine was originally banned for use in the United States but
was brought in to the country as a horse tranquilizer then
illegally transferred to tobacco farms for use in their product.
Chemistry >>
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Nicotine
History and name
Chemistry
Pharmacology
1.Pharmacokinetics
2.Pharmacodynamics
2.1 In adrenal medulla
2.2 In CNS
Psychoactive effects
Dependence
Toxicology
Therapeutic uses
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